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RANKL/RANK: from bone loss to the prevention of breast cancer

RANK and RANKL, a receptor ligand pair belonging to the tumour necrosis factor family, are the critical regulators of osteoclast development and bone metabolism. Besides their essential function in bone, RANK and RANKL have also been identified as the key factors for the formation of a lactating mam...

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Detalles Bibliográficos
Autores principales: Sigl, Verena, Jones, Laundette P., Penninger, Josef M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133443/
https://www.ncbi.nlm.nih.gov/pubmed/27881737
http://dx.doi.org/10.1098/rsob.160230