Human selenoprotein P and S variant mRNAs with different numbers of SECIS elements and inferences from mutant mice of the roles of multiple SECIS elements

Dynamic redefinition of the 10 UGAs in human and mouse selenoprotein P (Sepp1) mRNAs to specify selenocysteine instead of termination involves two 3′ UTR structural elements (SECIS) and is regulated by selenium availability. In addition to the previously known human Sepp1 mRNA poly(A) addition site...

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Detalles Bibliográficos
Autores principales: Wu, Sen, Mariotti, Marco, Santesmasses, Didac, Hill, Kristina E., Baclaocos, Janinah, Aparicio-Prat, Estel, Li, Shuping, Mackrill, John, Wu, Yuanyuan, Howard, Michael T., Capecchi, Mario, Guigó, Roderic, Burk, Raymond F., Atkins, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133445/
https://www.ncbi.nlm.nih.gov/pubmed/27881738
http://dx.doi.org/10.1098/rsob.160241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133445/
https://www.ncbi.nlm.nih.gov/pubmed/27881738
http://dx.doi.org/10.1098/rsob.160241

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