Cargando…

Hyperthermia enhances 17-DMAG efficacy in hepatocellular carcinoma cells with aggravated DNA damage and impaired G2/M transition

Due to the lack of effective treatment, hepatocellular carcinoma (HCC) is one of the malignancies with low survival rates worldwide. Combination of hyperthermia and chemotherapy has shown promising results in several abdominal tumours, but high expression of HSP90 in tumours attenuated the efficacy...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Zhizhou, Zhou, Xueqiong, He, Yangfan, Ke, Xiangyu, Wen, Ying, Zou, Fei, Chen, Xuemei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133462/
https://www.ncbi.nlm.nih.gov/pubmed/27909289
http://dx.doi.org/10.1038/srep38072