Cargando…
Hyperthermia enhances 17-DMAG efficacy in hepatocellular carcinoma cells with aggravated DNA damage and impaired G2/M transition
Due to the lack of effective treatment, hepatocellular carcinoma (HCC) is one of the malignancies with low survival rates worldwide. Combination of hyperthermia and chemotherapy has shown promising results in several abdominal tumours, but high expression of HSP90 in tumours attenuated the efficacy...
Autores principales: | Huang, Zhizhou, Zhou, Xueqiong, He, Yangfan, Ke, Xiangyu, Wen, Ying, Zou, Fei, Chen, Xuemei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133462/ https://www.ncbi.nlm.nih.gov/pubmed/27909289 http://dx.doi.org/10.1038/srep38072 |
Ejemplares similares
-
Hypoxia attenuates Hsp90 inhibitor 17-DMAG-induced cyclin B1 accumulation in hepatocellular carcinoma cells
por: Zhang, Jianming, et al.
Publicado: (2016) -
Population pharmacokinetic analysis of 17-dimethylaminoethylamino-17-demethoxygeldanamycin (17-DMAG) in adult patients with solid tumors
por: Aregbe, Abdulateef O., et al.
Publicado: (2012) -
Effects of 17-DMAG on diffuse large B-cell lymphoma cell apoptosis
por: Li, Jia-Jia, et al.
Publicado: (2017) -
17-DMAG regulates p21 expression to induce chondrogenesis in vitro and in vivo
por: Bertram, Karri L., et al.
Publicado: (2018) -
Development and Characterization of PLGA Nanoparticles Containing 17-DMAG, an Hsp90 Inhibitor
por: Cruz, Kercia P., et al.
Publicado: (2021)