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Using next-generation DNA sequence data for genetic association tests based on allele counts with and without consideration of zero inflation

The relationship between genetic variability and individual phenotypes is usually investigated by testing for association relying on called genotypes. Allele counts obtained from next-generation sequence data could be used for this purpose too. Genetic association can be examined by treating alterna...

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Detalles Bibliográficos
Autores principales: González Silos, Rosa, Karadag, Özge, Peil, Barbara, Fischer, Christine, Kabisch, Maria, Legrand, Carine, Lorenzo Bermejo, Justo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133473/
https://www.ncbi.nlm.nih.gov/pubmed/27980668
http://dx.doi.org/10.1186/s12919-016-0062-5