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Using next-generation DNA sequence data for genetic association tests based on allele counts with and without consideration of zero inflation
The relationship between genetic variability and individual phenotypes is usually investigated by testing for association relying on called genotypes. Allele counts obtained from next-generation sequence data could be used for this purpose too. Genetic association can be examined by treating alterna...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133473/ https://www.ncbi.nlm.nih.gov/pubmed/27980668 http://dx.doi.org/10.1186/s12919-016-0062-5 |