Identifying regions of disease-related variants in admixed populations with the summation partition approach

We propose a new method for identifying disease-related regions of single nucleotide variants in recently admixed populations. We use principal component analysis to derive both global and local ancestry information. We then use the summation partition approach to search for disease-related regions...

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Detalles Bibliográficos
Autores principales: Auerbach, Jonathan, Agne, Michael, Fan, Rachel, Lo, Adeline, Lo, Shaw-Hwa, Zheng, Tian, Wang, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133488/
https://www.ncbi.nlm.nih.gov/pubmed/27980624
http://dx.doi.org/10.1186/s12919-016-0018-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133488/
https://www.ncbi.nlm.nih.gov/pubmed/27980624
http://dx.doi.org/10.1186/s12919-016-0018-9

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