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Finding potential cis-regulatory loci using allele-specific chromatin accessibility as weights in a kernel-based variance component test
We present a novel approach to detect potential cis-acting regulatory loci that combines the functional potential, an empirical DNase-seq based estimate of the allele-specificity of DNase-I hypersensitivity sites, with kernel-based variance component association analyses against expression phenotype...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133489/ https://www.ncbi.nlm.nih.gov/pubmed/27980619 http://dx.doi.org/10.1186/s12919-016-0013-1 |