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Comparing strategies for combined testing of rare and common variants in whole sequence and genome-wide genotype data
We used our extension of the kernel score test to family data to analyze real and simulated baseline systolic blood pressure in extended pedigrees. We compared the power for different kernels and for different weightings of genetic markers. Moreover, we compared the power of rare and common markers...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133495/ https://www.ncbi.nlm.nih.gov/pubmed/27980648 http://dx.doi.org/10.1186/s12919-016-0042-9 |