Causal effect estimation in sequencing studies: a Bayesian method to account for confounder adjustment uncertainty

Estimating the causal effect of a single nucleotide variant (SNV) on clinical phenotypes is of interest in many genetic studies. The effect estimation may be confounded by other SNVs as a result of linkage disequilibrium as well as demographic and clinical characteristics. Because a large number of...

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Detalles Bibliográficos
Autores principales: Wang, Chi, Liu, Jinpeng, Fardo, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133506/
https://www.ncbi.nlm.nih.gov/pubmed/27980670
http://dx.doi.org/10.1186/s12919-016-0064-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133506/
https://www.ncbi.nlm.nih.gov/pubmed/27980670
http://dx.doi.org/10.1186/s12919-016-0064-3

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