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Causal effect estimation in sequencing studies: a Bayesian method to account for confounder adjustment uncertainty
Estimating the causal effect of a single nucleotide variant (SNV) on clinical phenotypes is of interest in many genetic studies. The effect estimation may be confounded by other SNVs as a result of linkage disequilibrium as well as demographic and clinical characteristics. Because a large number of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133506/ https://www.ncbi.nlm.nih.gov/pubmed/27980670 http://dx.doi.org/10.1186/s12919-016-0064-3 |