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A clustering approach to identify rare variants associated with hypertension

With the development of the next-generation sequencing technology, the influence of rare variants on complex disease has gathered increasing attention. In this paper, we propose a clustering-based approach, the clustering sum test, to test the effects of rare variants association by using the simula...

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Detalles Bibliográficos
Autores principales: Sun, Rui, Deng, Qiao, Hu, Inchi, Zee, Benny Chung-Ying, Wang, Maggie Haitian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133508/
https://www.ncbi.nlm.nih.gov/pubmed/27980628
http://dx.doi.org/10.1186/s12919-016-0022-0