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Testing rare variants for hypertension using family-based tests with different weighting schemes

Next-generation sequencing technology makes directly testing rare variants possible. However, existing statistical methods to detect common variants may not be optimal for testing rare variants because of allelic heterogeneity as well as the extreme rarity of individual variants. Recently, several s...

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Detalles Bibliográficos
Autores principales: Wang, Xuexia, Zhao, Xingwang, Zhou, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133509/
https://www.ncbi.nlm.nih.gov/pubmed/27980642
http://dx.doi.org/10.1186/s12919-016-0036-7