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Testing rare variants for hypertension using family-based tests with different weighting schemes
Next-generation sequencing technology makes directly testing rare variants possible. However, existing statistical methods to detect common variants may not be optimal for testing rare variants because of allelic heterogeneity as well as the extreme rarity of individual variants. Recently, several s...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133509/ https://www.ncbi.nlm.nih.gov/pubmed/27980642 http://dx.doi.org/10.1186/s12919-016-0036-7 |