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Comparison of 2 models for gene–environment interactions: an example of simulated gene–medication interactions on systolic blood pressure in family-based data

BACKGROUND: Nearly half of adults in the United States who are diagnosed with hypertension use blood-pressure-lowering medications. Yet there is a large interindividual variability in the response to these medications. Two complementary gene–environment interaction methods have been published and in...

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Detalles Bibliográficos
Autores principales: Fernández-Rhodes, Lindsay, Hodonsky, Chani J., Graff, Mariaelisa, Love, Shelly-Ann M., Howard, Annie Green, Seyerle, Amanda A., Avery, Christy L., Chittoor, Geetha, Franceschini, Nora, Voruganti, V. Saroja, Young, Kristin, O’Connell, Jeffrey R., North, Kari E., Justice, Anne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133512/
https://www.ncbi.nlm.nih.gov/pubmed/27980664
http://dx.doi.org/10.1186/s12919-016-0058-1