The impact of genetic structure on sequencing analysis

BACKGROUND: Genome-wide association studies have made substantial progress in identifying common variants associated with human diseases. Despite such success, a large portion of heritability remains unexplained. Evolutionary theory and empirical studies suggest that rare mutations could play an imp...

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Detalles Bibliográficos
Autores principales: Jadhav, Sneha, Vsevolozhskaya, Olga A., Tong, Xiaoran, Lu, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133514/
https://www.ncbi.nlm.nih.gov/pubmed/27980631
http://dx.doi.org/10.1186/s12919-016-0025-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133514/
https://www.ncbi.nlm.nih.gov/pubmed/27980631
http://dx.doi.org/10.1186/s12919-016-0025-x

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