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The impact of genetic structure on sequencing analysis
BACKGROUND: Genome-wide association studies have made substantial progress in identifying common variants associated with human diseases. Despite such success, a large portion of heritability remains unexplained. Evolutionary theory and empirical studies suggest that rare mutations could play an imp...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133514/ https://www.ncbi.nlm.nih.gov/pubmed/27980631 http://dx.doi.org/10.1186/s12919-016-0025-x |