Incorporation of protein binding effects into likelihood ratio test for exome sequencing data

Statistical association studies are an important tool in detecting novel disease genes. However, for sequencing data, association studies confront the challenge of low power because of relatively small data sample size and rare variants. Incorporating biological information that reflects disease mec...

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Detalles Bibliográficos
Autores principales: Zhang, Dongni, Cui, Hongzhu, Korkin, Dmitry, Wu, Zheyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133515/
https://www.ncbi.nlm.nih.gov/pubmed/27980649
http://dx.doi.org/10.1186/s12919-016-0043-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133515/
https://www.ncbi.nlm.nih.gov/pubmed/27980649
http://dx.doi.org/10.1186/s12919-016-0043-8

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