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Comparing family-based rare variant association tests for dichotomous phenotypes

BACKGROUND: It has been repeatedly stressed that family-based samples suffer less from genetic heterogeneity and that association analyses with family-based samples are expected to be powerful for detecting susceptibility loci for rare disease. Various approaches for rare-variant analysis with famil...

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Detalles Bibliográficos
Autores principales: Wang, Longfei, Choi, Sungkyoung, Lee, Sungyoung, Park, Taesung, Won, Sungho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133528/
https://www.ncbi.nlm.nih.gov/pubmed/27980633
http://dx.doi.org/10.1186/s12919-016-0027-8