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Comparing family-based rare variant association tests for dichotomous phenotypes
BACKGROUND: It has been repeatedly stressed that family-based samples suffer less from genetic heterogeneity and that association analyses with family-based samples are expected to be powerful for detecting susceptibility loci for rare disease. Various approaches for rare-variant analysis with famil...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133528/ https://www.ncbi.nlm.nih.gov/pubmed/27980633 http://dx.doi.org/10.1186/s12919-016-0027-8 |