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Improved in-cell structure determination of proteins at near-physiological concentration

Investigating three-dimensional (3D) structures of proteins in living cells by in-cell nuclear magnetic resonance (NMR) spectroscopy opens an avenue towards understanding the structural basis of their functions and physical properties under physiological conditions inside cells. In-cell NMR provides...

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Detalles Bibliográficos
Autores principales: Ikeya, Teppei, Hanashima, Tomomi, Hosoya, Saori, Shimazaki, Manato, Ikeda, Shiro, Mishima, Masaki, Güntert, Peter, Ito, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133543/
https://www.ncbi.nlm.nih.gov/pubmed/27910948
http://dx.doi.org/10.1038/srep38312