Engineering of a thermostable esterase Est816 to improve its quorum-quenching activity and the underlying structural basis

N-acyl-homoserine lactones (AHLs) are small diffusible molecules called autoinducers that mediate cell-to-cell communications. Enzymatic degradation of AHLs is a promising bio-control strategy known as quorum-quenching. To improve the quorum-quenching activity of a thermostable esterase Est816, whic...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Xiwen, Cao, Li-chuang, Fan, Xin-jiong, Liu, Yu-huan, Xie, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133562/
https://www.ncbi.nlm.nih.gov/pubmed/27909291
http://dx.doi.org/10.1038/srep38137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133562/
https://www.ncbi.nlm.nih.gov/pubmed/27909291
http://dx.doi.org/10.1038/srep38137

Ejemplares similares