The mechanism of transactivation regulation due to polymorphic short tandem repeats (STRs) using IGF1 promoter as a model

Functional short tandem repeats (STR) are polymorphic in the population, and the number of repeats regulates the expression of nearby genes (known as expression STR, eSTR). STR in IGF1 promoter has been extensively studied for its association with IGF1 concentration in blood and various clinical tra...

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Detalles Bibliográficos
Autores principales: Chen, Holly Y., Ma, Suk Ling, Huang, Wei, Ji, Lindan, Leung, Vincent H. K., Jiang, Honglin, Yao, Xiaoqiang, Tang, Nelson L. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133613/
https://www.ncbi.nlm.nih.gov/pubmed/27910883
http://dx.doi.org/10.1038/srep38225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133613/
https://www.ncbi.nlm.nih.gov/pubmed/27910883
http://dx.doi.org/10.1038/srep38225

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