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Microtubule stabilising peptides rescue tau phenotypes in-vivo

The microtubule cytoskeleton is a highly dynamic, filamentous network underpinning cellular structure and function. In Alzheimer’s disease, the microtubule cytoskeleton is compromised, leading to neuronal dysfunction and eventually cell death. There are currently no disease-modifying therapies to sl...

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Detalles Bibliográficos
Autores principales: Quraishe, Shmma, Sealey, Megan, Cranfield, Louise, Mudher, Amritpal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133624/
https://www.ncbi.nlm.nih.gov/pubmed/27910888
http://dx.doi.org/10.1038/srep38224