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Microtubule stabilising peptides rescue tau phenotypes in-vivo
The microtubule cytoskeleton is a highly dynamic, filamentous network underpinning cellular structure and function. In Alzheimer’s disease, the microtubule cytoskeleton is compromised, leading to neuronal dysfunction and eventually cell death. There are currently no disease-modifying therapies to sl...
Autores principales: | Quraishe, Shmma, Sealey, Megan, Cranfield, Louise, Mudher, Amritpal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133624/ https://www.ncbi.nlm.nih.gov/pubmed/27910888 http://dx.doi.org/10.1038/srep38224 |
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