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Single nucleotide-level mapping of DNA double-strand breaks in human HEK293T cells

Constitutional biological processes involve the generation of DNA double-strand breaks (DSBs). The production of such breaks and their subsequent resolution are also highly relevant to neurodegenerative diseases and cancer, in which extensive DNA fragmentation has been described Stephens et al. (201...

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Detalles Bibliográficos
Autores principales: Pope, Bernard J., Mahmood, Khalid, Jung, Chol-hee, Georgeson, Peter, Park, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133665/
https://www.ncbi.nlm.nih.gov/pubmed/27942458
http://dx.doi.org/10.1016/j.gdata.2016.11.007