Multiparameter mechanical and morphometric screening of cells

We introduce a label-free method to rapidly phenotype and classify cells purely based on physical properties. We extract 15 biophysical parameters from cells as they deform in a microfluidic stretching flow field via high-speed microscopy and apply machine-learning approaches to discriminate differe...

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Detalles Bibliográficos
Autores principales: Masaeli, Mahdokht, Gupta, Dewal, O’Byrne, Sean, Tse, Henry T. K., Gossett, Daniel R., Tseng, Peter, Utada, Andrew S., Jung, Hea-Jin, Young, Stephen, Clark, Amander T., Di Carlo, Dino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133672/
https://www.ncbi.nlm.nih.gov/pubmed/27910869
http://dx.doi.org/10.1038/srep37863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133672/
https://www.ncbi.nlm.nih.gov/pubmed/27910869
http://dx.doi.org/10.1038/srep37863

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