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Multiparameter mechanical and morphometric screening of cells
We introduce a label-free method to rapidly phenotype and classify cells purely based on physical properties. We extract 15 biophysical parameters from cells as they deform in a microfluidic stretching flow field via high-speed microscopy and apply machine-learning approaches to discriminate differe...
Autores principales: | Masaeli, Mahdokht, Gupta, Dewal, O’Byrne, Sean, Tse, Henry T. K., Gossett, Daniel R., Tseng, Peter, Utada, Andrew S., Jung, Hea-Jin, Young, Stephen, Clark, Amander T., Di Carlo, Dino |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133672/ https://www.ncbi.nlm.nih.gov/pubmed/27910869 http://dx.doi.org/10.1038/srep37863 |
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