RBM5 reduces small cell lung cancer growth, increases cisplatin sensitivity and regulates key transformation-associated pathways

Small cell lung cancer (SCLC) is the most aggressive type of lung cancer, with almost 95% of patients succumbing to the disease. Although RBM5, a tumor suppressor gene, is downregulated in the majority of lung cancers, its role in SCLC is unknown. Using the GLC20 SCLC cell line, which has a homozygo...

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Detalles Bibliográficos
Autores principales: Loiselle, Julie J., Roy, Justin G., Sutherland, Leslie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133678/
https://www.ncbi.nlm.nih.gov/pubmed/27957556
http://dx.doi.org/10.1016/j.heliyon.2016.e00204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133678/
https://www.ncbi.nlm.nih.gov/pubmed/27957556
http://dx.doi.org/10.1016/j.heliyon.2016.e00204

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