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Genetic factors influencing risk to orofacial clefts: today’s challenges and tomorrow’s opportunities

Orofacial clefts include cleft lip (CL), cleft palate (CP), and cleft lip and palate (CLP), which combined represent the largest group of craniofacial malformations in humans with an overall prevalence of one per 1,000 live births. Each of these birth defects shows strong familial aggregation, sugge...

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Detalles Bibliográficos
Autores principales: Beaty, Terri H., Marazita, Mary L., Leslie, Elizabeth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133690/
https://www.ncbi.nlm.nih.gov/pubmed/27990279
http://dx.doi.org/10.12688/f1000research.9503.1