Total synthesis of feglymycin based on a linear/convergent hybrid approach using micro-flow amide bond formation

Feglymycin is a naturally occurring, anti-HIV and antimicrobial 13-mer peptide that includes highly racemizable 3,5-dihydroxyphenylglycines (Dpgs). Here we describe the total synthesis of feglymycin based on a linear/convergent hybrid approach. Our originally developed micro-flow amide bond formatio...

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Detalles Bibliográficos
Autores principales: Fuse, Shinichiro, Mifune, Yuto, Nakamura, Hiroyuki, Tanaka, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133696/
https://www.ncbi.nlm.nih.gov/pubmed/27892469
http://dx.doi.org/10.1038/ncomms13491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133696/
https://www.ncbi.nlm.nih.gov/pubmed/27892469
http://dx.doi.org/10.1038/ncomms13491

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