Cargando…

Modulation of mRNA and lncRNA expression dynamics by the Set2–Rpd3S pathway

H3K36 methylation by Set2 targets Rpd3S histone deacetylase to transcribed regions of mRNA genes, repressing internal cryptic promoters and slowing elongation. Here we explore the function of this pathway by analysing transcription in yeast undergoing a series of carbon source shifts. Approximately...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Ji Hyun, Lee, Bo Bae, Oh, Young Mi, Zhu, Chenchen, Steinmetz, Lars M., Lee, Yookyeong, Kim, Wan Kyu, Lee, Sung Bae, Buratowski, Stephen, Kim, TaeSoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133700/
https://www.ncbi.nlm.nih.gov/pubmed/27892458
http://dx.doi.org/10.1038/ncomms13534