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Modulation of mRNA and lncRNA expression dynamics by the Set2–Rpd3S pathway
H3K36 methylation by Set2 targets Rpd3S histone deacetylase to transcribed regions of mRNA genes, repressing internal cryptic promoters and slowing elongation. Here we explore the function of this pathway by analysing transcription in yeast undergoing a series of carbon source shifts. Approximately...
Autores principales: | Kim, Ji Hyun, Lee, Bo Bae, Oh, Young Mi, Zhu, Chenchen, Steinmetz, Lars M., Lee, Yookyeong, Kim, Wan Kyu, Lee, Sung Bae, Buratowski, Stephen, Kim, TaeSoo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133700/ https://www.ncbi.nlm.nih.gov/pubmed/27892458 http://dx.doi.org/10.1038/ncomms13534 |
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