Cargando…

Wnt5a induces renal AQP2 expression by activating calcineurin signalling pathway

Heritable nephrogenic diabetes insipidus (NDI) is characterized by defective urine concentration mechanisms in the kidney, which are mainly caused by loss-of-function mutations in the vasopressin type 2 receptor. For the treatment of heritable NDI, novel strategies that bypass the defective vasopres...

Descripción completa

Detalles Bibliográficos
Autores principales: Ando, Fumiaki, Sohara, Eisei, Morimoto, Tetsuji, Yui, Naofumi, Nomura, Naohiro, Kikuchi, Eriko, Takahashi, Daiei, Mori, Takayasu, Vandewalle, Alain, Rai, Tatemitsu, Sasaki, Sei, Kondo, Yoshiaki, Uchida, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133730/
https://www.ncbi.nlm.nih.gov/pubmed/27892464
http://dx.doi.org/10.1038/ncomms13636