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Antibody responses to de novo identified citrullinated fibrinogen peptides in rheumatoid arthritis and visualization of the corresponding B cells
BACKGROUND: Antibodies against citrullinated proteins (ACPA) are common in patients with rheumatoid arthritis (RA). ACPA can appear before disease onset and target many self-antigens. Citrullinated fibrin/fibrinogen represents a classical ACPA target antigen, and mass spectrometry of RA synovial flu...
Autores principales: | Joshua, Vijay, Schobers, Loes, Titcombe, Philip J., Israelsson, Lena, Rönnelid, Johan, Hansson, Monika, Catrina, Anca I., Pruijn, Ger J. M., Malmström, Vivianne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133744/ https://www.ncbi.nlm.nih.gov/pubmed/27906052 http://dx.doi.org/10.1186/s13075-016-1181-0 |
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