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Age-Related Modulations of AQP4 and Caveolin-1 in the Hippocampus Predispose the Toxic Effect of Phoneutria nigriventer Spider Venom

We have previously demonstrated that Phoneutria nigriventer venom (PNV) causes blood–brain barrier (BBB) breakdown, swelling of astrocytes end-feet and fluid permeation into brain interstitium in rats. Caveolae and water channels respond to BBB alterations by co-participation in shear stress respons...

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Detalles Bibliográficos
Autores principales: Soares, Edilene S., Stávale, Leila M., Mendonça, Monique C. P., Coope, Andressa, da Cruz-Höfling, Maria Alice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133769/
https://www.ncbi.nlm.nih.gov/pubmed/27886057
http://dx.doi.org/10.3390/ijms17111462