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Assessing Heterogeneity of Osteolytic Lesions in Multiple Myeloma by (1)H HR-MAS NMR Metabolomics

Multiple myeloma (MM) is a malignancy of plasma cells characterized by multifocal osteolytic bone lesions. Macroscopic and genetic heterogeneity has been documented within MM lesions. Understanding the bases of such heterogeneity may unveil relevant features of MM pathobiology. To this aim, we deplo...

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Detalles Bibliográficos
Autores principales: Tavel, Laurette, Fontana, Francesca, Garcia Manteiga, Josè Manuel, Mari, Silvia, Mariani, Elisabetta, Caneva, Enrico, Sitia, Roberto, Camnasio, Francesco, Marcatti, Magda, Cenci, Simone, Musco, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133815/
https://www.ncbi.nlm.nih.gov/pubmed/27809247
http://dx.doi.org/10.3390/ijms17111814