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Effect of High-Carbohydrate Diet on Plasma Metabolome in Mice with Mitochondrial Respiratory Chain Complex III Deficiency

Mitochondrial disorders cause energy failure and metabolic derangements. Metabolome profiling in patients and animal models may identify affected metabolic pathways and reveal new biomarkers of disease progression. Using liver metabolomics we have shown a starvation-like condition in a knock-in (Bcs...

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Detalles Bibliográficos
Autores principales: Rajendran, Jayasimman, Tomašić, Nikica, Kotarsky, Heike, Hansson, Eva, Velagapudi, Vidya, Kallijärvi, Jukka, Fellman, Vineta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133825/
https://www.ncbi.nlm.nih.gov/pubmed/27809283
http://dx.doi.org/10.3390/ijms17111824