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USP19-Mediated Deubiquitination Facilitates the Stabilization of HRD1 Ubiquitin Ligase

In the endoplasmic reticulum (ER), misfolded and unfolded proteins are eliminated by a process called ER-associated protein degradation (ERAD) in order to maintain cell homeostasis. In the ERAD pathway, several ER-localized E3 ubiquitin ligases target ERAD substrate proteins for ubiquitination and s...

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Detalles Bibliográficos
Autores principales: Harada, Kumi, Kato, Masako, Nakamura, Nobuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133830/
https://www.ncbi.nlm.nih.gov/pubmed/27827840
http://dx.doi.org/10.3390/ijms17111829