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USP19-Mediated Deubiquitination Facilitates the Stabilization of HRD1 Ubiquitin Ligase
In the endoplasmic reticulum (ER), misfolded and unfolded proteins are eliminated by a process called ER-associated protein degradation (ERAD) in order to maintain cell homeostasis. In the ERAD pathway, several ER-localized E3 ubiquitin ligases target ERAD substrate proteins for ubiquitination and s...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133830/ https://www.ncbi.nlm.nih.gov/pubmed/27827840 http://dx.doi.org/10.3390/ijms17111829 |