Salvianolic Acid B (Sal B) Protects Retinal Pigment Epithelial Cells from Oxidative Stress-Induced Cell Death by Activating Glutaredoxin 1 (Grx1)

Protein glutathionylation, defined as the formation of protein mixed disulfides (PSSG) between cysteine residues and glutathione (GSH), can lead to cell death. Glutaredoxin 1 (Grx1) is a thiol repair enzyme which catalyzes the reduction of PSSG. Therefore, Grx1 exerts strong anti-apoptotic effects b...

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Detalles Bibliográficos
Autores principales: Liu, Xiaobin, Xavier, Christy, Jann, Jamieson, Wu, Hongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133836/
https://www.ncbi.nlm.nih.gov/pubmed/27827892
http://dx.doi.org/10.3390/ijms17111835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133836/
https://www.ncbi.nlm.nih.gov/pubmed/27827892
http://dx.doi.org/10.3390/ijms17111835

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