IBTK Differently Modulates Gene Expression and RNA Splicing in HeLa and K562 Cells

The IBTK gene encodes the major protein isoform IBTKα that was recently characterized as substrate receptor of Cul3-dependent E3 ligase, regulating ubiquitination coupled to proteasomal degradation of Pdcd4, an inhibitor of translation. Due to the presence of Ankyrin-BTB-RCC1 domains that mediate se...

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Detalles Bibliográficos
Autores principales: Fiume, Giuseppe, Scialdone, Annarita, Rizzo, Francesca, De Filippo, Maria Rosaria, Laudanna, Carmelo, Albano, Francesco, Golino, Gaetanina, Vecchio, Eleonora, Pontoriero, Marilena, Mimmi, Selena, Ceglia, Simona, Pisano, Antonio, Iaccino, Enrico, Palmieri, Camillo, Paduano, Sergio, Viglietto, Giuseppe, Weisz, Alessandro, Scala, Giuseppe, Quinto, Ileana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133848/
https://www.ncbi.nlm.nih.gov/pubmed/27827994
http://dx.doi.org/10.3390/ijms17111848

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133848/
https://www.ncbi.nlm.nih.gov/pubmed/27827994
http://dx.doi.org/10.3390/ijms17111848

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