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NOD Scid Gamma Mice Are Permissive to Allogeneic HSC Transplantation without Prior Conditioning

Scid hematopoietic stem cells (HSCs) have an intrinsic defect in their maintenance within the bone marrow (BM) niche which facilitates HSC transplantation without the absolute requirement of prior conditioning. Nevertheless, NOD scid mice have a significantly altered life span due to early developme...

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Detalles Bibliográficos
Autores principales: Verbiest, Tom, Finnon, Rosemary, Brown, Natalie, Finnon, Paul, Bouffler, Simon, Badie, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133850/
https://www.ncbi.nlm.nih.gov/pubmed/27827995
http://dx.doi.org/10.3390/ijms17111850