Brefeldin A-Inhibited Guanine Nucleotide-Exchange Factor 1 (BIG1) Governs the Recruitment of Tumor Necrosis Factor Receptor-Associated Factor 2 (TRAF2) to Tumor Necrosis Factor Receptor 1 (TNFR1) Signaling Complexes

Tumor necrosis factor receptor-associated factor 2 (TRAF2) is a critical mediator of tumor necrosis factor-α (TNF-α) signaling. However, the regulatory mechanisms of TRAF2 are not fully understood. Here we show evidence that TRAF2 requires brefeldin A-inhibited guanine nucleotide-exchange factor 1 (...

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Detalles Bibliográficos
Autores principales: Noguchi, Takuya, Tsuchida, Mei, Kogue, Yosuke, Spadini, Christian, Hirata, Yusuke, Matsuzawa, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133869/
https://www.ncbi.nlm.nih.gov/pubmed/27834853
http://dx.doi.org/10.3390/ijms17111869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133869/
https://www.ncbi.nlm.nih.gov/pubmed/27834853
http://dx.doi.org/10.3390/ijms17111869

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