Berberine Suppresses Cyclin D1 Expression through Proteasomal Degradation in Human Hepatoma Cells

The aim of this study is to explore the underlying mechanism on berberine-induced Cyclin D1 degradation in human hepatic carcinoma. We observed that berberine could suppress both in vitro and in vivo expression of Cyclin D1 in hepatoma cells. Berberine exhibits dose- and time-dependent inhibition on...

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Detalles Bibliográficos
Autores principales: Wang, Ning, Wang, Xuanbin, Tan, Hor-Yue, Li, Sha, Tsang, Chi Man, Tsao, Sai-Wah, Feng, Yibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133898/
https://www.ncbi.nlm.nih.gov/pubmed/27854312
http://dx.doi.org/10.3390/ijms17111899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133898/
https://www.ncbi.nlm.nih.gov/pubmed/27854312
http://dx.doi.org/10.3390/ijms17111899

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