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The Vitamin E Analog Gamma-Tocotrienol (GT3) and Statins Synergistically Up-Regulate Endothelial Thrombomodulin (TM)

Statins; a class of routinely prescribed cholesterol-lowering drugs; inhibit 3-hydroxy-3-methylglutaryl-coenzymeA reductase (HMGCR) and strongly induce endothelial thrombomodulin (TM); which is known to have anti-inflammatory; anti-coagulation; anti-oxidant; and radioprotective properties. However;...

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Detalles Bibliográficos
Autores principales: Pathak, Rupak, Ghosh, Sanchita P., Zhou, Daohong, Hauer-Jensen, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133932/
https://www.ncbi.nlm.nih.gov/pubmed/27869747
http://dx.doi.org/10.3390/ijms17111937