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Loss of Rictor with aging in osteoblasts promotes age-related bone loss

Osteoblast dysfunction is a major cause of age-related bone loss, but the mechanisms underlying changes in osteoblast function with aging are poorly understood. This study demonstrates that osteoblasts in aged mice exhibit markedly impaired adhesion to the bone formation surface and reduced minerali...

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Detalles Bibliográficos
Autores principales: Lai, Pinling, Song, Qiancheng, Yang, Cheng, Li, Zhen, Liu, Sichi, Liu, Bin, Li, Mangmang, Deng, Hongwen, Cai, Daozhang, Jin, Dadi, Liu, Anling, Bai, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133960/
https://www.ncbi.nlm.nih.gov/pubmed/27735936
http://dx.doi.org/10.1038/cddis.2016.249