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Hypoxia-induced expression of cellular prion protein improves the therapeutic potential of mesenchymal stem cells
Mesenchymal stem cells (MSCs) are ‘adult' multipotent cells that promote regeneration of injured tissues in vivo. However, differences in oxygenation levels between normoxic culture conditions (21% oxygen) and both the MSC niche (2–8% oxygen) and ischemic injury-induced oxidative stress conditi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133977/ https://www.ncbi.nlm.nih.gov/pubmed/27711081 http://dx.doi.org/10.1038/cddis.2016.310 |