Loss of XIAP facilitates switch to TNFα-induced necroptosis in mouse neutrophils

Neutrophils are essential players in the first-line defense against invading bacteria and fungi. Besides its antiapoptotic role, the inhibitor of apoptosis protein (IAP) family member X-linked IAP (XIAP) has been shown to regulate innate immune signaling. Whereas the role of XIAP in innate signaling...

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Detalles Bibliográficos
Autores principales: Wicki, Simone, Gurzeler, Ursina, Wei-Lynn Wong, W, Jost, Philipp J, Bachmann, Daniel, Kaufmann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133978/
https://www.ncbi.nlm.nih.gov/pubmed/27735938
http://dx.doi.org/10.1038/cddis.2016.311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133978/
https://www.ncbi.nlm.nih.gov/pubmed/27735938
http://dx.doi.org/10.1038/cddis.2016.311

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