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Methamphetamine potentiates HIV-1 gp120-mediated autophagy via Beclin-1 and Atg5/7 as a pro-survival response in astrocytes

Methamphetamine (METH), a commonly used controlled substance, is known to exacerbate neuropathological dysfunction in HIV-infected individuals. The neuropathological manifestation results from cell death or dysfunction in the central nervous system (CNS) wherein autophagy is expected to have an impo...

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Detalles Bibliográficos
Autores principales: Cao, Lu, Fu, Mingui, Kumar, Santosh, Kumar, Anil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133984/
https://www.ncbi.nlm.nih.gov/pubmed/27763640
http://dx.doi.org/10.1038/cddis.2016.317