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Transactivation of TrkB by Sigma-1 receptor mediates cocaine-induced changes in dendritic spine density and morphology in hippocampal and cortical neurons

Cocaine is a highly addictive narcotic associated with dendritic spine plasticity in the striatum. However, it remains elusive whether cocaine modifies spines in a cell type-specific or region-specific manner or whether it alters different types of synapses in the brain. In addition, there is a pauc...

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Detalles Bibliográficos
Autores principales: Ka, Minhan, Kook, Yeon-Hee, Liao, Ke, Buch, Shilpa, Kim, Woo-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133986/
https://www.ncbi.nlm.nih.gov/pubmed/27735948
http://dx.doi.org/10.1038/cddis.2016.319